Ethical Considerations: Growth Hormone Treatment in Children with Idiopathic Short Stature

Parent Requests Growth Hormone for Child With Idiopathic Short Stature Pediatrics. ,vol. 114, pp. 1478- 1482 ,(2004) , 10.1542/PEDS.2004-1721P

Beth S. Finkelstein, Thomas F. Imperiale, Theodore Speroff, Ursula Marrero, Deborah J. Radcliffe, Leona Cuttler, Effect of growth hormone therapy on height in children with idiopathic short stature: a meta-analysis. JAMA Pediatrics. ,vol. 156, pp. 230- 240 ,(2002) , 10.1001/ARCHPEDI.156.3.230

Dina Pilpel, Frank J. Leavitt, Esther Elizur-Leiberman, Ethical and cross cultural questions concerning pediatric clinical trials Controlled Clinical Trials. ,vol. 17, pp. 201- 208 ,(1996) , 10.1016/0197-2456(95)00256-1

M. Todd Miller, Michael D. Pasquale, William J. Bromberg, Thomas E. Wasser, John Cox, Not so FAST. Journal of Trauma-injury Infection and Critical Care. ,vol. 54, pp. 52- 60 ,(2003) , 10.1097/00005373-200301000-00007

Jan M. Wit, Lyset T.M. Rekers-Mombarg, Gordon B. Cutler, Brenda Crowe, Tracy J. Beck, Kristen Roberts, Anne Gill, Jean-Louis Chaussain, Herwig Frisch, Rafael Yturriaga, Andrea F. Attanasio, Growth hormone (GH) treatment to final height in children with idiopathic short stature: Evidence for a dose effect The Journal of Pediatrics. ,vol. 146, pp. 45- 53 ,(2005) , 10.1016/J.JPEDS.2004.08.055

J. M. Wit, L. T. M. Rekers-Mombarg, Final height gain by GH therapy in children with idiopathic short stature is dose dependent. The Journal of Clinical Endocrinology and Metabolism. ,vol. 87, pp. 604- 611 ,(2002) , 10.1210/JCEM.87.2.8225

Michael Freemark, Editorial: Growth Hormone Treatment of “Idiopathic Short Stature”: Not So Fast The Journal of Clinical Endocrinology and Metabolism. ,vol. 89, pp. 3138- 3139 ,(2004) , 10.1210/JC.2004-0671

Tom L. Beauchamp, James Franklin Childress, Principles of biomedical ethics ,(1979)

Meir Lampit, Ze’ev Hochberg, Prevention of Growth Deceleration after Withdrawal of Growth Hormone Therapy in Idiopathic Short Stature The Journal of Clinical Endocrinology and Metabolism. ,vol. 87, pp. 3573- 3577 ,(2002) , 10.1210/JCEM.87.8.8721

David E Sandberg, William M Bukowski, Caroline M Fung, Robert B Noll, Height and social adjustment: are extremes a cause for concern and action? Pediatrics. ,vol. 114, pp. 744- 750 ,(2004) , 10.1542/PEDS.2003-1169-L