THREE NEW QUASSINOID DERIVATIVES AND RELATED COMPOUNDS AS ANTITUMOR PROMOTERS FROM BRUCEA JAVANICA
作者： Shakila Rahman , Narihiko Fukamiya , Harukuni Tokuda , Hoyoku Nishino , Kiyoshi Tagahara
DOI: 10.1246/BCSJ.72.751
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摘要: Three new quassinoid derivatives [desmethyl-brusatol (1), desmethyl- bruceantinoside A (2), and butyl ester (3) of bruceoside D (6)] were isolated from the extract Brucea javanica. Their structures elucidated by spectral evidence chemical transformation to or known compounds. The three related compounds have shown inhibitory effects against TPA-induced Epstein–Barr virus early antigen (EBV-EA) activation.
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