Goats' milk as a natural source of lactose-derived oligosaccharides: Isolation by membrane technology

作者: Antonio Martinez-Ferez , Silvia Rudloff , Antonio Guadix , Cordula A. Henkel , Gottfried Pohlentz

DOI: 10.1016/J.IDAIRYJ.2005.02.003

关键词:

摘要: Abstract Human milk oligosaccharides are thought to be beneficial for the infant with regard their prebiotic and anti-infective properties. However, so far no from farm animals has been considered a good natural source of lactose-derived human nutrition. In this study, characterization quantitation neutral sialylated in mature caprine was performed compared ovine, bovine milk. The quantification carried out using high-pH anion-exchange chromatography pulsed amperometric detection (HPAEC-PAD), by fast atom bombardment mass spectrometry (FAB-MS). A large amount variety acidic were found goats’ when cow sheep addition, 15 new oligosaccharide structures identified order isolate fraction, two-stage tangential ultrafiltration–nanofiltration process selected. Tubular ceramic membranes molecular cut-offs 50 1 kDa, respectively, employed. virtually lactose salts-free product containing more than 80% original content obtained.

参考文章(33)
Christopher D. Warren, Prasoon Chaturvedi, Adrienne R. Newburg, Olav T. Oftedal, Christopher D. Tilde, David S. Newburg, Comparison of oligosaccharides in milk specimens from humans and twelve other species. Advances in Experimental Medicine and Biology. ,vol. 501, pp. 325- 332 ,(2001) , 10.1007/978-1-4615-1371-1_40
Akira Kobata, Victor Ginsburg, Oligosaccharides of Human Milk: III. ISOLATION AND CHARACTERIZATION OF A NEW HEXASACCHARIDE, LACTO-N-HEXAOSE Journal of Biological Chemistry. ,vol. 247, pp. 1525- 1529 ,(1972) , 10.1016/S0021-9258(19)45589-0
David S. Newburg, Bioactive Components of Human Milk Advances in Experimental Medicine and Biology. ,vol. 501, pp. 3- 10 ,(2001) , 10.1007/978-1-4615-1371-1_1
Ronald S Kirk, Ronald Sawyer, Pearson's Composition and Analysis of Foods ,(1990)
Mark J. Gnoth, Clemens Kunz, Evamaria Kinne-Saffran, Silvia Rudloff, Human Milk Oligosaccharides Are Minimally Digested In Vitro Journal of Nutrition. ,vol. 130, pp. 3014- 3020 ,(2000) , 10.1093/JN/130.12.3014
C. Kunz, S. Rudloff, W. Baier, N. Klein, S. Strobel, Oligosaccharides in Human Milk: Structural, Functional, and Metabolic Aspects Annual Review of Nutrition. ,vol. 20, pp. 699- 722 ,(2000) , 10.1146/ANNUREV.NUTR.20.1.699
A. Cravioto, A. Tello, H. Villafan, J. Ruiz,, S. del Vedovo, J.-R. Neeser, Inhibition of Localized Adhesion of Enteropathogenic Escherichia coli to HEp-2 Cells by Immunoglobulin and Oligosaccharide Fractions of Human Colostrum and Breast Milk The Journal of Infectious Diseases. ,vol. 163, pp. 1247- 1255 ,(1991) , 10.1093/INFDIS/163.6.1247