A new method for experimental study on gastric mucosal damage
作者： Saburo Nakazawa , Kosei Segawa , Kenji Imai , Masafumi Aichi , Yoshihisa Tsukamoto
DOI: 10.1007/BF02774933
关键词:
摘要: We have demonstrated development of mucosal damage in rats maintained a hypoxic condition. The gastric lesions were observed only the corpus ventriculi almost all cases, and they rated as U1-1 erosions histopathologically. method has proven to facilitate induction long-sustained, stable hypoxemia any desired degree animals is concluded be appropriate for an experimental model ulceration designed study defensive mechanisms.
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sci-hub.se 参考文章(4)
Keijiro Takagi, Yutaka Kasuya, Kazuo Watanabe, Studies on the Drugs for Peptic Ulcer. A Reliable Method for Producing Stress Ulcer in Rats. Chemical & Pharmaceutical Bulletin. ,vol. 12, pp. 465- 472 ,(1964) , 10.1248/CPB.12.465
S.N.S. Murthy, Vicente P. Dinoso, Harris R. Clearfield, William Y. Chey, Serial pH Changes in the Duodenal Bulb During Smoking Gastroenterology. ,vol. 75, pp. 1- 4 ,(1978) , 10.1016/0016-5085(78)93754-X
Pekka-T. Harjola, Arto Sivula, Gastric ulceration following experimentally induced hypoxia and hemorrhagic shock: in vivo study of pathogenesis in rabbits. Annals of Surgery. ,vol. 163, pp. 21- 28 ,(1966) , 10.1097/00000658-196601000-00003
René Menguy, Y.F. Masters, Mechanism of stress ulcer. IV. Influence of fasting on the tolerance of gastric mucosal energy metabolism to ischemia and on the incidence of stress ulceration. Gastroenterology. ,vol. 66, pp. 1177- 1186 ,(1974) , 10.1016/S0016-5085(74)80010-7