Effects of Acute Plasma Volume Expansion on Maternal Renal and Central Hemodynamics and Atrial Natriuretic Peptide Concentrations in Normal and Preeclamptic Pregnancies
作者： Marius Kublickas , Charlotta Grunewald , Kjell Carlstrom , Henry Niselld , Ivar Randmaa
DOI: 10.3109/10641959609009593
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摘要: Objective: To evaluate the maternal renal hemodynamic response to acute plasma volume expansion in normal and hypertensive pregnancies, relate it changes central hemodynamics atrial natriuretic peptide (ANP) concentrations.Methods: Seven women with pregnancy-induced hypertension (PIH)/ preeclampsia 10 healthy pregnant controls last trimester were studied. Renal Doppler echocardiographic investigations performed, venous blood was sampled for determination of ANP concentrations before after 30 min infusion a crystalloid solution (15 mL/kg).Results: Baseline artery pulsatility index (PI) did not differ between group (1.10 ± 0.13, mean SD) PIH/preeclampsia (1.12 0.08). After PI increased (P < 0.01) 1.43 0.23 group, but remained unchanged group. expansion, both PIH/preeclamptic showed an increase cardiac output stro...
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