Efficacy and safety of Monascus purpureus Went rice in subjects with secondary hyperlipidemia

摘要: Background/aims Nephrotic dyslipidemia is a risk factor for the development of systemic atherosclerosis; it may also aggravate glomerulosclerosis and enhance progression glomerular disease. We aimed to assess efficacy safety Monascus purpureus Went rice versus fluvastatin therapy in management nephrotic dyslipidemia. Methods In total 72 patients with idiopathic persistent NS secondary were included. They randomly allocated into three age- sex-matched groups. The first group comprised 20 cases that given M. dose 600 mg twice per day one month then once daily. second 30 daily mg. remaining 22 received no antidyslipidemic constituted control group. All these subjected thorough laboratory investigations, including renal function tests lipograms. Moreover, neuromuscular status was evaluated electromyography nerve conduction velocity. Results Our results showed both well-tolerated evidence significant side effects, on function. Both significantly reduced cholesterol after six months year, respectively. Conclusion safe, effective economic treatment strategy