Molecular detection of chromosome aberrations

作者: Anthonie Willem Langerak , Jacobus Johannus Maria van Dongen

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摘要: The invention relates to the field of cytogenetics and application genetic diagnostic techniques in pathology hematology. Specifically, nucleic acid probes that can be used hybridization for detection chromosomal aberrations other gene rearrangements such as immunoglobulin T-cell receptor rearrangements. provided by are a distinct balanced set comparable size, each preferably being from 1 100 kb, or smaller, flanking potential breakpoint chromosome.

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