Alteration between inhibition and stimulation in individual and mixture effects of [amim]Br and [apyr]Br on Aliivibrio fischeri: Time and side-chain dependence
作者： Ning Sui , Zhiguo Zhang , Jing Zhang
DOI: 10.1016/J.CHEMOSPHERE.2019.05.279
关键词:
摘要: The exposure reality of chemicals is usually in mixtures, the effects which are extrapolated from individual results. Yet, such extrapolation challenged by alteration between monotonic concentration-response curves (CRCs) and non-monotonic hormetic CRCs mixture effects. In present study, we aimed to investigate occurrence alterations using 1-alkylimidazolium bromide ([amim]Br) 1-alkylpyridinium ([apyr]Br) ionic liquids (ILs) as model chemicals. Effects four [amim]Br, [apyr]Br, their quaternary mixtures designed uniform design were measured on Aliivibrio fischeri a time-dependent fashion. Results showed that [amim]Br CRCs. Their inhibition increased over length side-chain decreased time. CRCs, where stimulations [apyr]Br had stimulation side-chain. Meanwhile, without any stimulation. Notably, positive contributors [emim]Br or [epyr]Br shortest among components. findings can facilitate accurate prediction environmental ILs with specific considerations
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