Quinazolinone-benzimidazole conjugates: Synthesis, characterization, dihydrofolate reductase inhibition, DNA and protein binding properties.
作者： Prinka Singla , Vijay Luxami , Kamaldeep Paul
DOI: 10.1016/J.JPHOTOBIOL.2017.02.009
关键词:
摘要: … Compounds are then evaluated by dihydrofolate reductase inhibitory activity. In … dihydrofolate reductase inhibitory activities. Compound 14 shows comparable or even superior inhibitory …
sci-hub.se 参考文章(62)
Daniel C. Carter, Joseph X. Ho, Structure of serum albumin. Advances in Protein Chemistry. ,vol. 45, pp. 153- 203 ,(1994) , 10.1016/S0065-3233(08)60640-3
Smitha Antony, Keli K. Agama, Ze-Hong Miao, Melinda Hollingshead, Susan L. Holbeck, Mollie H. Wright, Lyuba Varticovski, Muthukaman Nagarajan, Andrew Morrell, Mark Cushman, Yves Pommier, Bisindenoisoquinoline bis-1,3-{(5,6-dihydro-5,11-diketo-11H-indeno[1,2-c]isoquinoline)-6-propylamino}propane bis(trifluoroacetate) (NSC 727357), a DNA intercalator and topoisomerase inhibitor with antitumor activity. Molecular Pharmacology. ,vol. 70, pp. 1109- 1120 ,(2006) , 10.1124/MOL.106.024372
Prinka Singla, Vijay Luxami, Kamaldeep Paul, Benzimidazole-biologically attractive scaffold for protein kinase inhibitors RSC Advances. ,vol. 4, pp. 12422- 12440 ,(2014) , 10.1039/C3RA46304D
Manishkumar B. Patel, Uma Harikrishnan, Nikunj N. Valand, Nishith R. Modi, Shobhana K. Menon, Novel cationic quinazolin-4(3H)-one conjugated fullerene nanoparticles as antimycobacterial and antimicrobial agents. Archiv Der Pharmazie. ,vol. 346, pp. 210- 220 ,(2013) , 10.1002/ARDP.201200371
Yasuo TAKEUCHI, Midori KOIKE, Kumiko AZUMA, Hiromi NISHIOKA, Hitoshi ABE, Hye-Sook KIM, Yusuke WATAYA, Takashi HARAYAMA, Synthesis and antimalarial activity of febrifugine derivatives. Chemical & Pharmaceutical Bulletin. ,vol. 49, pp. 721- 725 ,(2001) , 10.1248/CPB.49.721
Xiao-Le Han, Ping Mei, Yi Liu, Qi Xiao, Feng-Lei Jiang, Ran Li, Binding interaction of quinclorac with bovine serum albumin: a biophysical study. Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy. ,vol. 74, pp. 781- 787 ,(2009) , 10.1016/J.SAA.2009.08.018
Balasubramanian Narasimhan, Deepika Sharma, Pradeep Kumar, Benzimidazole: a medicinally important heterocyclic moiety Medicinal Chemistry Research. ,vol. 21, pp. 269- 283 ,(2012) , 10.1007/S00044-010-9533-9
Dawei Lu, Xingchen Zhao, Yingcan Zhao, Bingcong Zhang, Bin Zhang, Mengyang Geng, Rutao Liu, Binding of Sudan II and Sudan IV to bovine serum albumin: comparison studies. Food and Chemical Toxicology. ,vol. 49, pp. 3158- 3164 ,(2011) , 10.1016/J.FCT.2011.09.011
Laurence H. Hurley, DNA and its associated processes as targets for cancer therapy Nature Reviews Cancer. ,vol. 2, pp. 188- 200 ,(2002) , 10.1038/NRC749
Ajit K. Parhi, Yongzheng Zhang, Kurt W. Saionz, Padmanava Pradhan, Malvika Kaul, Kalkal Trivedi, Daniel S. Pilch, Edmond J. LaVoie, Antibacterial activity of quinoxalines, quinazolines, and 1,5-naphthyridines Bioorganic & Medicinal Chemistry Letters. ,vol. 23, pp. 4968- 4974 ,(2013) , 10.1016/J.BMCL.2013.06.048