Differential expression of two gap junction proteins in corneal epithelium

摘要: Two distinct gap junction proteins (connexins) are expressed in rat corneal epithelium a way which parallels cellular differentiation processes this tissue. Connexin43 is restricted predominantly to the basal cells of and present significantly reduced amounts compared situation adjacent conjunctival epithelium. In contrast, protein recognized by antibodies against MP70 ovine homolog mouse connexin50, strongly cells, wing surface cells. While functional significance differential expression epithelial connexins has yet be established, third avascular tissue besides lens heart valves expresses anti-MP70 antibodies.