Full-length TDP-43 forms toxic amyloid oligomers that are present in frontotemporal lobar dementia-TDP patients

作者: Yu-Sheng Fang , Kuen-Jer Tsai , Yu-Jen Chang , Patricia Kao , Rima Woods

DOI: 10.1038/NCOMMS5824

关键词:

摘要: … We also provided evidence that these oligomers are present in the transgenic TDP-43 mice and FTLD-TDP patients. Our results suggest that TDP-43 oligomers are part of TDP-43 …

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