Ex vivo lung evaluation and reconditioning

作者: Paulo Manuel Pêgo-Fernandes , Alessandro Wasum Mariani , Israel Lopes de Medeiros , Artur Eugenio de Azevedo Pereira , Flávio Guimarães Fernandes

DOI: 10.1590/S0102-76382010000400006

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摘要: Objective: Only about 15% of the potential candidates for lung donation are considered suitable transplantation. A new method ex vivo perfusion (EVLP) has been developed and can be used evaluation reconditioning “marginal” unacceptable lungs. This is a report functional experience with twelve donor lungs deemed in Sao Paulo, Brazil. Methods: After harvesting, perfused Steen Solution, an extra-cellular solution high colloid osmotic pressure. membrane oxygenator connected to circuit receives gas from mixture nitrogen carbon dioxide maintains normal mixed venous blood level perfusate. The gradually rewarmed, reperfused ventilated. They evaluated through

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