Characterization of overoxidized polypyrrole colloids imprinted with L-lactate and their application to enantioseparation of amino acids.

摘要: Overoxidized polypyrrole colloids imprinted with l-lactate were prepared to evaluate the performance of overoxidation pseudo-template technique developed by authors. A colloid that had been from a mixture monomer (pyrrole), dopant (l-lactate), steric stabilizer (poly(vinylpyrrolidone)) and oxidizing agent (peroxodisulfate) was electrochemically overoxidized at +1.5 V vs Ag|AgCl create complementary cavity for recognition molecules, which structurally similar dopant, through dedoping. As target molecule enantioselective uptake into colloid, we selected alanine, is different template (lactate) only in one side chain (alanine, −NH2; lactic acid, −OH). The showed higher affinity l-alanine than d-alanine, an ratio (l/d) as high 11 ± 4 observed under optimum conditions. Uptake reached equilibrium 10 min, thanks surface area short ...