Modelling the Transmission of Trypanosoma cruzi: The Need for an Integrated Genetic Epidemiological and Population Genomics Approach

作者: Michel Tibayrenc

DOI: 10.1007/978-1-4419-6064-1_14

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摘要: This chapter describes what should be an integrated approach to the genetic epidemiology and population genomics of Chagas disease. Many studies have been conducted on diversity Trypanosoma cruzi various triatomine bug species able transmit Far less research has analyzed role played by host’s variability transmission severity An epidemiology/population would analyze these three components chain together as well their possible interactions (co-evolution phenomena). is facilitated recent impressive progress in mega biotechnologies fact that disease ideal model for experimental evolution approaches.

参考文章(75)
Marta de Lana, Artur da Silveira Pinto, Christian Barnabé, Virginie Quesney, Sébastien Noël, Michel Tibayrenc, Trypanosoma cruzi: compared vectorial transmissibility of three major clonal genotypes by Triatoma infestans. Experimental Parasitology. ,vol. 90, pp. 20- 25 ,(1998) , 10.1006/EXPR.1998.4304
Paulo MM Guedes, Vanja M Veloso, Marcelo V Caliari, Cláudia M Carneiro, Sheler M Souza, Marta De Lana, Egler Chiari, Maria T Bahia, Lúcia Galvão, None, Trypanosoma cruzi high infectivity in vitro is related to cardiac lesions during long-term infection in Beagledogs Memorias Do Instituto Oswaldo Cruz. ,vol. 102, pp. 141- 147 ,(2007) , 10.1590/S0074-02762007005000003
Ricardo P Souto, Octavio Fernandes, Andréa M Macedo, David A Campbell, Bianca Zingales, DNA markers define two major phylogenetic lineages of Trypanosoma cruzi Molecular and Biochemical Parasitology. ,vol. 83, pp. 141- 152 ,(1996) , 10.1016/S0166-6851(96)02755-7
Sylvain Brisse, Christian Barnabé, Michel Tibayrenc, Identification of six Trypanosoma cruzi phylogenetic lineages by random amplified polymorphic DNA and multilocus enzyme electrophoresis. International Journal for Parasitology. ,vol. 30, pp. 35- 44 ,(2000) , 10.1016/S0020-7519(99)00168-X
Antonieta Rojas de Arias, Michael A. Miles, Michael W. Gaunt, Matthew Yeo, Iain A. Frame, J. Russell Stothard, Hernan J. Carrasco, Martin C. Taylor, Susana Solis Mena, Paul Veazey, Graham A. J. Miles, Nidia Acosta, Mechanism of genetic exchange in American trypanosomes Nature. ,vol. 421, pp. 936- 939 ,(2003) , 10.1038/NATURE01438
VINCENT PAYET, FRÉDÉRIC TRIPET, GREGORY LANZARO, FRÉDÉRIC MENU, MARIA JESUS RAMIREZ-SIERRA, ERIC DUMONTEIL, Assessment of Triatoma dimidiata dispersal in the Yucatan Peninsula of Mexico by morphometry and microsatellite markers. American Journal of Tropical Medicine and Hygiene. ,vol. 76, pp. 930- 937 ,(2007) , 10.4269/AJTMH.2007.76.930
Richard Bellamy, Nulda Beyers, Keith PWJ McAdam, Cyril Ruwende, Robert Gie, Priscilla Samaai, Danite Bester, Mandy Meyer, Tumani Corrah, Matthew Collin, D Ross Camidge, David Wilkinson, Eileen Hoal-van Helden, Hilton C Whittle, William Amos, Paul Van Helden, Adrian VS Hill, Genetic susceptibility to tuberculosis in Africans: A genome-wide scan Proceedings of the National Academy of Sciences of the United States of America. ,vol. 97, pp. 8005- 8009 ,(2000) , 10.1073/PNAS.140201897
R. P. Oliveira, N. E. Broude, A. M. Macedo, C. R. Cantor, C. L. Smith, S. D. J. Pena, Probing the genetic population structure of Trypanosoma cruzi with polymorphic microsatellites Proceedings of the National Academy of Sciences of the United States of America. ,vol. 95, pp. 3776- 3780 ,(1998) , 10.1073/PNAS.95.7.3776
M.J.de O Toledo, M de Lana, C.M Carneiro, M.T Bahia, G.L.L Machado-Coelho, V.M Veloso, C Barnabé, M Tibayrenc, W.L Tafuri, Impact of Trypanosoma cruzi clonal evolution on its biological properties in mice. Experimental Parasitology. ,vol. 100, pp. 161- 172 ,(2002) , 10.1016/S0014-4894(02)00003-6