Probiotics and prebiotics in prevention and treatment of diseases in infants and children.

摘要: Objective: To evaluate the impact of probiotics and prebiotics on health children. Sources: MEDLINE LILACS were searched for relevant English French-language articles. Summary findings: Human milk is rich in prebiotic oligosaccharides may contain some probiotics. No data suggest that addition to infant formula be harmful, but evidence its efficacy insufficient recommendation. Since specific reduce infections atopy healthy infants, their seems reasonable. Long-term benefits pro- developing immune system remain proven. Selected duration infectious diarrhea by 1 day, prevention lacking, except antibiotic-associated diarrhea. Some prevent necrotizing enterocolitis, other microorganisms beneficial Helicobacter pylori gastritis infantile colic. Evidence recommend treatment atopic dermatitis. The use constipation, irritable bowel syndrome, inflammatory disease, extra-intestinal requires more studies. Conclusions: Duration administration, microbial dosage, species used need further validation both prebiotics. Unjustified claims are a major threat concept.