Primary pancreatic lymphoma: Report of six cases

摘要: AIM: To heighten recognition of primary pancreatic lymphoma (PPL) in clinical practice. METHODS: A retrospective review the presentation, imaging characteristics and pathological features PPL patients were presented, as well their diagnosis treatment, combination with literature review. RESULTS: Histological was made four by surgery two EUS-FNA. The six (5 males 1 female; age range, 16-65 years; mean age, 46 years) had duration symptoms for weeks to three months. presenting symptoms, though not characteristic, abdominal pain, masses, weight loss, jaundice, nausea vomiting. One developed acute pancreatitis. In one patient, level serum CA19-9 76.3 μg/L. Abdominal CT scan showed that tumors located head pancreas, body tail, throughout pancreas. Diameter pancreas cases more than 6 cm, homogeneous density unclear borders. Enhanced only tumor edges slightly enhanced. duct irregularly narrowed whose body, which endoscopic retrograde cholangiopancreatography (ERCP) proximal segment dilated. Two underwent Whipple operation, patient pancreatectomy, another operative biliary decompression. stageIE 2 stage II E 4 according Ann Arbor classification system. B-cell non-Hodgkin’s all histopathologically. All systemic chemotherapy, whom also treated gamma radiometry. died after diagnosis, lost follow-up, who received chemotherapy survived 49 37 mo, remaining is still alive 21 treatment. CONCLUSION: a rare form extranodal originating from parenchyma. Clinical findings are otherwise specific differentiation cancer, deserves attention. EUS-guided fine-needle aspiration (EUS-FNA) requires experienced cytopathologists advanced immunohistochemical assays obtain final on small amount tissue. Surgery adjuvant or radiotherapy can produce fairly good outcomes.