Factors associated with the treatment of latent tuberculosis infection among health-care workers at a midwestern teaching hospital.

摘要: Study objective To assess factors associated with initiating therapy and compliance treatment for latent tuberculosis infection among health-care workers positive tuberculin skin test results. Design Prospective cohort study. Setting An urban midwestern teaching hospital in St. Louis, MO. population Health-care Measurements (1) Rates of all results, (2) rates recent conversion. Results A total 440 test-positive were evaluated from January 1, 1994, to May 2000. Of those evaluated, 1 worker had presumed active tuberculosis, no record being missing records, 33 not recommended isoniazid therapy, leaving 404 analysis. Overall, 396 (98%) results initiated therapy. In univariate analysis, bacille Calmette-Guerin (BCG) vaccination (p = 0.02) foreign birth 0.03) significantly Compliance data available 388 (96%). these, 318 (82%) compliant 6 months BCG (odds ratio [OR], 3.5; 95% confidence interval [CI], 1.8 7.1) symptoms while receiving (OR, 4.5; CI, 2.0 10.1) noncompliance multivariate Among new converters, Asian race 0.006), 0.01), Conclusion This a high rate their workers, These initiation completion much higher than previously reported the literature. may be largely due focused program, which includes follow-up consisting physician counseling monthly phone consultations by nurses, along free services medications provided on-site.