Synthesis, characterization, and biological activity of organotin(IV) complexes with 4-oxo-4-[3-(trifluoromethyl)phenylamino]butanoic acid
作者： F. Javed , S. Ali , S. Shahzadi , S. K. Sharma , K. Qanungo
DOI: 10.1134/S1070363217100231
关键词:
摘要: Metal complexes display functional interfaces for association with and stimulation of certain enzymes, that are liable to transfer genetic information in DNA synthesis specific proteins. Biological activity five organotin carboxylates based on the ligand, 4-oxo-4-[3-(trifluoromethyl)phenylamino]butanoic acid, such as [Bu3SnL] (1), [Ph3SnL] (2), [Me2SnL2] (3), [Bu2SnL2] (4), [Ph2SnL2] (5) have been synthesized their biological a function substitution ligand was tested. Structure evaluated by elemental analysis, FT-IR 1H, 13C NMR spectra. data theoretical calculations revieled acted bidentate 1–5. revealed four six coordinated geometry tin solutions. The HOMO–LUMO study indicated thermodynamic stability complexes. AFM confirmed catalytic potential screening showed that, few exceptions, all exhibited significant against various bacterial fungal strains. UV-Vis its binded via intercalative interactions.
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