Deposition of radiogallium (Ga72) in proliferating tissues.

作者: H. C. Dudley , G. W. Imirie , J. T. Istock

DOI: 10.1148/55.4.571

关键词:

摘要: It has previously been shown, chemically and autoradiographically, that gallium enters bone at a rapid rate, following injection of the citrate or lactate, concentrating in those areas considered to have marked osteogenic activity (1, 2, 3). The purpose present investigation was study experimental animals deposition radiogallium (Ga72) proliferating tissues. work comprised three parts: (a) quantitative determination amount Ga72 deposited normal growing healing fractures, (b) pilot degree certain neoplastic conditions, (c) development technics provide greater detail autoradiographs tissue containing Ga72. isotopes which appear greatest promise for biological studies are (14.3 hours half-life, 2.5 mev γ, 3.1 β−) Ga67 (78.3 K capture, 0.3 γ with conversion e−). can be prepared by neutron bombardment magnetically separated G...

参考文章(4)
Katherine E. Henry, J. I. Munn, H. C. Dudley, STUDIES OF THE METABOLISM OF GALLIUM Journal of Pharmacology and Experimental Therapeutics. ,vol. 98, pp. 105- 110 ,(1949)
H. C. Dudley, DETERMINATION OF GALLIUM IN BIOLOGICAL MATERIALS Journal of Pharmacology and Experimental Therapeutics. ,vol. 95, pp. 482- 486 ,(1949)