Synthetic and Structure-Activity Relationship Studies on Bioactive Natural Products
作者： Kouji KURAMOCHI
DOI: 10.1271/BBB.120884
关键词:
摘要: This review summarizes our research into the synthesis and structure-activity relationships of epolactaene, neoechinulin A, plakevulin pseudodeflectusin ustusorane C. These natural products are attractive in view their apoptosis-inducing activity, cytoprotective activity against peroxynitrite, inhibitory DNA polymerases, cytotoxicity cancer cells.
sci-hub.se 参考文章(84)
David E. Van Horn, Louis F. Valente, Michael J. Idacavage, Ei-Ichi Negishi, Controlled carbometallation : II. The addition reaction of trimethylalane-titanocene dichloride with acetylenes Journal of Organometallic Chemistry. ,vol. 156, ,(1978) , 10.1016/S0022-328X(00)84891-3
Scott E. Schaus, Bridget D. Brandes, Jay F. Larrow, Makoto Tokunaga, Karl B. Hansen, Alexandra E. Gould, Michael E. Furrow, Eric N. Jacobsen, Highly Selective Hydrolytic Kinetic Resolution of Terminal Epoxides Catalyzed by Chiral (salen)CoIII Complexes. Practical Synthesis of Enantioenriched Terminal Epoxides and 1,2-Diols Journal of the American Chemical Society. ,vol. 124, pp. 1307- 1315 ,(2002) , 10.1021/JA016737L
Wen-Liang Wang, Zhen-Yu Lu, Hong-Wen Tao, Tian-Jiao Zhu, Yu-Chun Fang, Qian-Qun Gu, Wei-Ming Zhu, Isoechinulin-type alkaloids, variecolorins A-L, from halotolerant Aspergillus variecolor. Journal of Natural Products. ,vol. 70, pp. 1558- 1564 ,(2007) , 10.1021/NP070208Z
Kouji Kuramochi, Fumiyo Saito, Ryo Takeuchi, Tomohiro Era, Masaharu Takemura, Jun'ichi Kobayashi, Kengo Sakaguchi, Susumu Kobayashi, Fumio Sugawara, Synthesis of plakevulin A and structure–activity relationships of its related compounds against DNA polymerases Tetrahedron. ,vol. 62, pp. 8006- 8015 ,(2006) , 10.1016/J.TET.2006.06.023
Yuna Sato, Kouji Kuramochi, Takahiro Suzuki, Atsuo Nakazaki, Susumu Kobayashi, The second generation synthesis of (+)-pseudodeflectusin Tetrahedron Letters. ,vol. 52, pp. 626- 629 ,(2011) , 10.1016/J.TETLET.2010.11.153
Kongkiat Trisuwan, Vatcharin Rukachaisirikul, Yaowapa Sukpondma, Souwalak Phongpaichit, Sita Preedanon, Jariya Sakayaroj, Furo[3,2-h]isochroman, furo[3,2-h]isoquinoline, isochroman, phenol, pyranone, and pyrone derivatives from the sea fan-derived fungus Penicillium sp. PSU-F40 Tetrahedron. ,vol. 66, pp. 4484- 4489 ,(2010) , 10.1016/J.TET.2010.04.073
Arnaldo Dossena, Rosangela Marchelli, Andrea Pochini, New metabolites of Aspergillus amstelodami related to the biogenesis of neoechinulin Journal of The Chemical Society, Chemical Communications. pp. 771- 772 ,(1974) , 10.1039/C39740000771
Thomas. G. Rand, J. DiPenta, C. Robbins, J.D. Miller, Effects of low molecular weight fungal compounds on inflammatory gene transcription and expression in mouse alveolar macrophages. Chemico-Biological Interactions. ,vol. 190, pp. 139- 147 ,(2011) , 10.1016/J.CBI.2011.02.017
K. Maruyama, Protective properties of neoechinulin A against SIN-1-induced neuronal cell death. Journal of Biochemistry. ,vol. 136, pp. 81- 87 ,(2004) , 10.1093/JB/MVH103
Yujiro Hayashi, Koichi Narasaka, Asymmetric Total Synthesis of Epolactaene Chemistry Letters. ,vol. 1998, pp. 313- 314 ,(1998) , 10.1246/CL.1998.313