Organic semiconductor recognition complex and system

作者: Eric A Holwitt , Charles R Batishko , John L Alls , John G Bruno , Johnathan L Kiel

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摘要: In a recognition complex system, nucleic acid ligands comprising random DNA sequences are operatively coupled to an organic semiconductor and distributed so as form array of complexes. When unknown chemical or biological analyte is applied the array, electrical and/or photochemical properties one more complexes altered upon binding ligand analyte. The degree which change function affinity sequence for changes associated with whole, can be used unique signature identify certain embodiments, iterative process selection amplification that bind generate new greater specificity target analyte, produce high present invention also provides methods preparing using such neutralize

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