Cardiac glycoside compounds and antitumor application thereof

摘要: The invention belongs to the technical field of medicaments and in particular relates cardiac glycoside compounds with a general formula (I), as well derivatives, stereoisomers, racemic mixture or non-racemic stereoisomers pharmaceutically acceptable acid addition salts solvates, wherein R1 is CH3, CHO CH2OH; R2 H linear saccharide chain branched chain, formed by saccharides; these acids comprise inorganic like hydrochloric acid, sulfuric hydrobromic phosphoric nitric carbonic organic methanoic acetic succinic citric lactic fumaric tartaric benzoic p-methyl-benzenesulfonic methylsulphonic naphthalenesulfonic gluconic like. can be obtained separation from plants, Streptocaulon plant juventas griffithii, using multiple conventional separating means through synthesis, semisynthesis bioconversion means. These have excellent inhibiting treatment effects on tumor cells.