Some regulatory properties of 3-hydroxybutyrate dehydrogenase in frozen-thawed rat liver mitochondria.
作者： Yu.G. Kaminsky
DOI: 10.1016/0305-0491(85)90257-3
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摘要: Abstract 1. The influence of various organic acids on 3-hydroxybutyrate dehydrogenase activity in frozen-thawed rat liver mitochondira was studied. 2. Pyruvate and oxaloacetate were found to exert inhibitory effects, that apparently indirect ones. 3. Malonate appeared be a competitive inhibitor the enzyme, kinetic constants being comparable with those for enzyme preparations from other sources. 4. Physiological role malonate ketone body oxidation are discussed.
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