Frontiers in hormone therapy for male infertility.

摘要: For a significant number of couples worldwide, infertility is harsh reality. As specialists in male infertility, much our armamentarium lacks definitive, evidence-based therapies. years, we have relied on manipulation the hormonal axis to treat those men who help carry burden their partnerships. Indeed, factor sole component at least 20% couples. Further compounding this dilemma that 25% 50% males with no identifiable etiology and thus present true management conundrum. This manuscript an attempt clarify what therapies exist for treatment infertility. We reviewed relevant literature honing, focus anomalies subsequent impact fertility. Many discussed been utilized practice generations. Thus, article attempts provide support continued use current paradigm. Furthermore, recognize any review beckons discussion challenges await horizon. instance, there has interest restoring spermatogenesis after testosterone replacement therapy (TRT). explore adverse long-term spermatogenic outcomes associated TRT, which widespread will inevitably great challenge specialists. Moreover, discuss role varicocelectomy hypogonadism association between growth hormone (GH) fertility address presented by rising prevalence obesity.