Chemically Triggered Synthesis, Remodeling, and Degradation of Soft Materials.

摘要: Polymer topology dictates dynamic and mechanical properties of materials. For most polymers, is a static characteristic. In this article, we present strategy to chemically trigger changes in polymers response specific chemical stimulus. Starting with dimerized PEG hydrophobic linear materials, lightly cross-linked polymer, hydrogel, transformations into an amphiphilic random copolymers, three different hydrogel matrices were achieved via two controllable cross-linking reactions: reversible conjugate additions thiol–disulfide exchange. Significantly, all the before or after topological changes, can be triggered degrade thiol- amine-terminated small molecules. The polymeric morphologies their degradation herald new generation smart