Early Metabolic Evolution: Insights from Comparative Cellular Genomics

摘要: The use of small subunit rRNAs as molecular markers has led to universal phylogenies, in which all known organisms can be grouped one three major cell lineages, the eubacteria, archaeabacteria, and eukaryotic nucleocytoplasm, now referred domains Bacteria, Archaea, Eucarya, respectively (Woese et al., 1990). A description last common ancestor (LCA, i.e., cenancestor), these primary kingdoms may inferred from distribution homologous characters among its descendants. In conjunction with fragmentary information available other organisms, complete genome sequences public databases allow such characterizations, some cases even provide insights into nature cenancestor predecessors. Here we discuss basic assumptions strategies used approaches, apply them understanding evolutionary assemblage arginine biosynthesis. Additional aspects evolution metabolic routes have been discussed Pereto al. (1997).