Going Beyond VEGF Pathway Inhibition for Antiangiogenic Cancer Therapy: Is Inhibition of the PP2A/B55α Complex the Answer?

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Dai Fukumura, Jonas Kloepper, Zohreh Amoozgar, Dan G. Duda, Rakesh K. Jain, Enhancing cancer immunotherapy using antiangiogenics: opportunities and challenges. Nature Reviews Clinical Oncology. ,vol. 15, pp. 325- 340 ,(2018) , 10.1038/NRCLINONC.2018.29

Winson S. Ho, Herui Wang, Dominic Maggio, John S. Kovach, Qi Zhang, Qi Song, Francesco M. Marincola, John D. Heiss, Mark R. Gilbert, Rongze Lu, Zhengping Zhuang, Pharmacologic inhibition of protein phosphatase-2A achieves durable immune-mediated antitumor activity when combined with PD-1 blockade. Nature Communications. ,vol. 9, pp. 2126- 2126 ,(2018) , 10.1038/S41467-018-04425-Z