Erlotinib in advanced well-differentiated thymic carcinoma with overexpression of EGFR: a case report.
作者： Rebecca Pedersini , Emanuela Vattemi , Maria Rita Lusso , Guido Mazzoleni , Heinrich Ebner
DOI: 10.1177/030089160809400613
关键词:
摘要: Aims and background. Advanced chemorefractory epithelial thymic tumors are still a challenge in clinical oncology. A therapeutic approach targeting key molecular pathway could be the ideal solution neoplasm that can overexpress epidermal growth factor receptor (EGFR) component. Methods. patient with metastatic heavily pretreated carcinoma was evaluated for EGFR expression primary tumor. Results. Strong revealed by immunohistochemistry. The received erlotinib therapy but had obtained no response after four months of treatment. Conclusion. This preliminary experience suggests may not useful choice advanced carcinomas.
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