Competence of depressed patients for consent to research

摘要: OBJECTIVE: The capacities of depressed patients to consent research have been questioned by commentators who fear that the cognitive effects a disorder may impair subjects’ abilities protect their interests. This study used new instrument for assessing patients’ and examined performance, including relation between severity depression extent impairment. METHOD: Twenty-six female outpatients with major (assessed Schedule Affective Disorders Schizophrenia—Lifetime Version) enrolled in maintenance psychotherapy were recruited this project. Consent-related measured MacArthur Competence Assessment Tool—Clinical Research (MacCAT-CR) 1 week after intake again 8–10 weeks later. Depressive symptoms Hamilton Depression Rating Scale. RESULTS: Almost all subjects performed quite well on capacity measures maintained level performance over t...