Organic matrices in metazoan calcium carbonate skeletons: Composition, functions, evolution.

摘要: Calcium carbonate skeletal tissues in metazoans comprise a small quantity of occluded organic macromolecules, mostly proteins and polysaccharides that constitute the matrix. Because its functions modulating biomineralization process are well known, matrix has been extensively studied, successively via classical biochemical approaches, molecular biology and, recent years, transcriptomics proteomics. The optimistic view deposition calcium minerals requires limited number macromolecules challenged, last decade, by high-throughput approaches. Such approaches have made possible rapid identification large sets mineral-associated proteins, i.e., ‘skeletal repertoires’ or ‘skeletomes’, several calcifying animal models, ranging from sponges to echinoderms. One consequences this expanding set data is simple definition no longer possible. This increase available data, however, makes it easier compare repertoires, shedding light on fundamental evolutionary mechanisms affecting components.