Acute Hepatitis C: High Rate of Both Spontaneous and Treatment-Induced Viral Clearance

作者: J.Tilman Gerlach , Helmut M Diepolder , Reinhart Zachoval , Norbert H Gruener , Maria-Christina Jung

DOI: 10.1016/S0016-5085(03)00668-1

关键词:

摘要: … of acute hepatitis C has to take into account the high rate of … induced) in 91% of patients, and unnecessary treatment was … hepatitis C virus infection are unlikely to clear the infection …

参考文章(33)
Akinobu Takaki, Manfred Wiese, Geert Maertens, Erik Depla, Ulrike Seifert, Anke Liebetrau, Jeffery L. Miller, Michael P. Manns, Barbara Rehermann, Cellular immune responses persist and humoral responses decrease two decades after recovery from a single-source outbreak of hepatitis C Nature Medicine. ,vol. 6, pp. 578- 582 ,(2000) , 10.1038/75063
Shinn-Jang Hwang, Shou-Dong Lee, Cho-Yu Chan, Rei-Hwa Lu, Kwang-Juei Lo, A randomized controlled trial of recombinant interferon α-2b in the treatment of Chinese patients with acute post-transfusion hepatitis C Journal of Hepatology. ,vol. 21, pp. 831- 836 ,(1994) , 10.1016/S0168-8278(94)80246-7
James G. Donahue, Alvaro Muñoz, Paul M. Ness, Donald E. Brown, David H. Yawn, Hugh A. McAllister, Bruce A. Reitz, Kenrad E. Nelson, The Declining Risk of Post-Transfusion Hepatitis C Virus Infection The New England Journal of Medicine. ,vol. 327, pp. 369- 373 ,(1992) , 10.1056/NEJM199208063270601
Susumu Takano, Yoichi Satomura, Masao Omata, Effects of interferon beta on non-A, non-B acute hepatitis : a prospective, randomized, controlled-dose study Gastroenterology. ,vol. 107, pp. 805- 811 ,(1994) , 10.1016/0016-5085(94)90130-9
J.Tilman Gerlach, Helmut M. Diepolder, Maria–Christina Jung, Norbert H. Gruener, Winfried W. Schraut, Reinhart Zachoval, Robert Hoffmann, C.Albrecht Schirren, Teresa Santantonio, Gerd R. Pape, Recurrence of hepatitis C virus after loss of virus-specific CD4(+) T-cell response in acute hepatitis C. Gastroenterology. ,vol. 117, pp. 933- 941 ,(1999) , 10.1016/S0016-5085(99)70353-7
Sun-Lung Tsai, Young-Mao Chen, Ming-Huei Chen, Chao-Yuan Huang, I-Shyan Sheen, Chau-Ting Yeh, Jyh-Hsiung Huang, George C. Kuo, Yun-Fan Liaw, Hepatitis C virus variants circumventing cytotoxic T lymphocyte activity as a mechanism of chronicity Gastroenterology. ,vol. 115, pp. 954- 966 ,(1998) , 10.1016/S0016-5085(98)70268-9
U. Busch, H. Nitschko, Methods for the differentiation of microorganisms. Journal of Chromatography B: Biomedical Sciences and Applications. ,vol. 722, pp. 263- 278 ,(1999) , 10.1016/S0378-4347(98)00369-7
Elmar Jaeckel, Markus Cornberg, Heiner Wedemeyer, Teresa Santantonio, Julika Mayer, Myrga Zankel, Giuseppe Pastore, Manfred Dietrich, Christian Trautwein, Michael P. Manns, Treatment of Acute Hepatitis C with Interferon Alfa-2b The New England Journal of Medicine. ,vol. 345, pp. 1452- 1457 ,(2001) , 10.1056/NEJMOA011232
Jay H. Hoofnagle, Therapy for acute hepatitis C. The New England Journal of Medicine. ,vol. 345, pp. 1495- 1497 ,(2001) , 10.1056/NEJM200111153452013
E. Jenny Heathcote, Mitchell L. Shiffman, W. Graham E. Cooksley, Geoffrey M. Dusheiko, Samuel S. Lee, Luis Balart, Robert Reindollar, Rajender K. Reddy, Teresa L. Wright, Amy Lin, Joseph Hoffman, Jean De Pamphilis, Peginterferon alfa-2a in patients with chronic hepatitis C and cirrhosis. The New England Journal of Medicine. ,vol. 343, pp. 1673- 1680 ,(2000) , 10.1056/NEJM200012073432302