Soft hydrogel based on modified chitosan containing P. granatum peel extract and its nano-forms: Multiparticulate study on chronic wounds treatment
作者： Tamer I.M. Ragab , Ahmed A. Nada , Eman A. Ali , Al Shimaa Gamal Shalaby , Ahmed A.F. Soliman
DOI: 10.1016/J.IJBIOMAC.2019.05.156
关键词:
摘要: Punica granatum peel (PGP) is widely used in traditional medicinal purposes for chronic wounds owing to containing natural phenolics active components. In current study, active wound dressing hydrogel for chronic wound healing was prepared based on P. granatum peel crude extract (PGPC), ethyl acetate fraction (PGPEA) and their silver nanoforms (Ag-NPs). Methacrylated chitosan was synthesized as precursor to hydrogel and crosslinked by divinyl sulfone (DVS) in mild condition. Hydrogel was fully characterized by spectral …
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