作者: Katsuyuki Hotta , Hiroshi Ueoka
DOI: 10.1016/J.CRITREVONC.2005.01.006
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摘要: The goal of treatment for patients with advanced cancer is to prolong survival, control symptoms, and reduce disease-related complications. Despite the introduction many cytotoxic agents during past decade, only modest improvement in survival has been achieved. In order urgently improve these situations, new as well molecular-targeted are now under investigation. this article, we reviewed latest information regarding antitumor activity, toxicity, pharmacokinetics, clinical application agents.