Representation of African-Americans, Hispanics, and Whites in National Cancer Institute Cancer Treatment Trials

摘要: Background : The National Cancer Institute (NCI)-sponsored clinical trials cooperative groups place more than 25 000 American patients in treatment every year. Equal access and proportional representation of all races/ethnicities is desired. Purpose Our objectives were to evaluate the inclusion African-Americans, Hispanics, non-Hispanic whites NCI-sponsored determine if there racial/ethnic representation. Methods During period January 1, 1991, through June 30, 1994, 99 495 cancer enrolled declared themselves as black, white, or Hispanic (of any race). In analysis, participants NCI subdivided into three age birth 19 years, 20-49 50 years. composition each these was compared with makeup population cancer. Estimates number incident cases per year made for group within using data from Surveillance, Epidemiology, End Results (SEER) Program 1990 Census. percentage who that entered trials. Comparisons are also separately leukemia breast, colorectal, lung, prostate cancers. Among 0-19 years old, old older relatively blacks, It noted 70% aged estimated enter 4.0% 1.5% older. Conclusions Accrual generally parallels burden disease among whites. Implications This study shows are, a whole, racially/ethnically representative suggests equal