作者: Markus Veen , Andreas Reindl , Christine Lang , Mewes Böttner
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摘要: The present invention relates to the use of a microorganism belonging group lactic acid bacteria or mutant derivative thereof, characterized in that it is capable specifically binding bacterium mutans Streptococci, wherein specific (i) resistant heat treatment; and/or (ii) protease (iii) calcium-dependent; (iv) formed within pH range between 4.5 and 8.5; (v) presence saliva, for preparation an anticariogenic composition treatment prevention caries caused by Streptococci other than Streptococcus mutans. Preferably, can be assayed as follows: (a) growing said stationary phase; (b) mixing with which has been grown (c) incubating mixture obtained step under conditions allowing formation aggregates Streptococci; (d) detecting occurrence pellet. Another aspect method prophylaxis mutans, comprising administering mutant, derivative, analog fragment microorganism.