Low-blood pressure phenotype underpins the tendency to reflex syncope.

摘要: Background We hypothesized that cardiovascular physiology differs in reflex syncope patients compared with the general population, predisposing such individuals to vasovagal reflex. Methods In this multicohort cross-sectional study, we aggregate data of resting SBP, DBP, pulse pressure (PP) and heart rate (HR), collected from six community-based cohort studies (64 968 observations) those databases (6516 observations), subdivided by age decades sex. Results Overall, male syncope, SBP (-3.4 mmHg) PP (-9.2 were lower DBP (+2.8 HR (+5.1 bpm) higher than population; difference was at ages above 60 years. female individuals, (-6.0 (+4.7 (+4.5 differences less pronounced, becoming evident only Compared exhibited slower increase until 40 years, then demonstrated steeper continued throughout remaining life. Conclusion The prone demonstrate a different haemodynamic profile as characterized PP, reflecting reduced venous return stroke volume, suggesting activation compensatory mechanisms. Our contribute better understanding why some similar demographic characteristics develop others do not. Video abstract http://links.lww.com/HJH/B580.