Hypervariability of simple sequences as a general source for polymorphic DNA markers
作者： Diethard Tautz
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摘要: Short simple sequence stretches occur as highly repetitive elements in all eukaryotic genomes and partially also prokaryotes eubacteria. They are thought to arise by slippage like events working on randomly occurring internally stretches. This predicts that they should be generally hypervariable length. I have used the polymerase chain reaction (PCR) process show several chosen loci with different nucleotide composition from species extensive length polymorphisms. These polymorphisms (SSLP) may usefully exploited for identity testing, population studies, linkage analysis genome mapping.
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