Type-Restricted Neutralization of Molecular Clones of Human Immunodeficiency Virus
作者： D. Looney , A. Fisher , S. Putney , Rusche , R. Redfield
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摘要: In a study of the immunologic significance genetic diversity present within single isolates human immunodeficiency virus type 1 (HIV-1), neutralization viruses derived from molecular clones HIV-1 strain HTLV-IIIB by an extensive panel sera was compared. Sera HIV-1-infected patients and goats immunized with polyacrylamide gel-purified envelope glycoprotein (gp120), native gp120, or gp120-derived recombinant peptides, showed marked heterogeneity in neutralizing activity against these closely related viruses. The change amino acid residue gp120 may account for such "clonal restriction" activity.
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S Matsushita, M Robert-Guroff, J Rusche, A Koito, T Hattori, H Hoshino, K Javaherian, K Takatsuki, S Putney, Characterization of a human immunodeficiency virus neutralizing monoclonal antibody and mapping of the neutralizing epitope. Journal of Virology. ,vol. 62, pp. 2107- 2114 ,(1988) , 10.1128/JVI.62.6.2107-2114.1988
P L Nara, W G Robey, L O Arthur, D M Asher, A V Wolff, C J Gibbs, D C Gajdusek, P J Fischinger, Persistent infection of chimpanzees with human immunodeficiency virus: serological responses and properties of reisolated viruses. Journal of Virology. ,vol. 61, pp. 3173- 3180 ,(1987) , 10.1128/JVI.61.10.3173-3180.1987
A. Fisher, B Ensoli, L Ivanoff, M Chamberlain, S Petteway, L Ratner, R. Gallo, F Wong-Staal, The sor gene of HIV-1 is required for efficient virus transmission in vitro. Science. ,vol. 237, pp. 888- 893 ,(1987) , 10.1126/SCIENCE.3497453
Amanda G. Fisher, Enrico Collalti, Lee Ratner, Robert C. Gallo, Flossie Wong-Staal, A molecular clone of HTLV-III with biological activity. Nature. ,vol. 316, pp. 262- 265 ,(1985) , 10.1038/316262A0
AMANDA FISHER, LINDA L. JAGODZINSKI, HIROAKI MITSUYA, RUEY-SHYAN LIOU, ROBERT C. GALLO, FLOSSIE WONG-STAAL, LEE RATNER, Complete nucleotide sequences of functional clones of the AIDS virus AIDS Research and Human Retroviruses. ,vol. 3, pp. 57- 69 ,(1987) , 10.1089/AID.1987.3.57
L. Lasky, J. Groopman, C. Fennie, P. Benz, D. Capon, D. Dowbenko, G. Nakamura, W. Nunes, M. Renz, P. Berman, Neutralization of the AIDS retrovirus by antibodies to a recombinant envelope glycoprotein Science. ,vol. 233, pp. 209- 212 ,(1986) , 10.1126/SCIENCE.3014647
S Harada, Y Koyanagi, N Yamamoto, Infection of HTLV-III/LAV in HTLV-I-carrying cells MT-2 and MT-4 and application in a plaque assay Science. ,vol. 229, pp. 563- 566 ,(1985) , 10.1126/SCIENCE.2992081
Robin A. Weiss, Paul R. Clapham, Jonathan N. Weber, Angus G. Dalgleish, Lawrence A. Lasky, Phillip W. Berman, Variable and conserved neutralization antigens of human immunodeficiency virus Nature. ,vol. 324, pp. 572- 575 ,(1986) , 10.1038/324572A0
Shiu-Lok Hu, Patricia N. Fultz, Harold M. McClure, Jorg W. Eichberg, Elaine Kinney Thomas, Joyce Zarling, Mitra C. Singhal, Steven G. Kosowski, R. Brent Swenson, Daniel C. Anderson, George Todaro, Effect of immunization with a vaccinia-HIV env recombinant on HIV infection of chimpanzees. Nature. ,vol. 328, pp. 721- 723 ,(1987) , 10.1038/328721A0
Robin A. Weiss, Paul R. Clapham, Rachanee Cheingsong-Popov, Angus G. Dalgleish, Christopher A. Carne, Ian V. D. Weller, Richard S. Tedder, Neutralization of human T-lymphotropic virus type III by sera of AIDS and AIDS-risk patients. Nature. ,vol. 316, pp. 69- 72 ,(1985) , 10.1038/316069A0