Prenatal detection of cerebral lesions in a fetus with tuberous sclerosis

作者: M. Sgro , T. Barozzino , A. Toi , J. Johnson , M. Sermer

DOI: 10.1046/J.1469-0705.1999.14050356.X

关键词:

摘要: We report a newborn, diagnosed prenatally with both cardiac rhabdomyomas and brain tumor. To the best of our knowledge, this is first central nervous system (CNS) lesions detected in child tuberous sclerosis term follow-up. At 36 months, has normal growth developing appropriately. Thus finding CNS tumors on fetal ultrasound examination can help prenatal diagnosis but does not necessarily indicate poor prognosis.

参考文章(14)
James F. Gusella, David J. Kwiatkowski, Susan A. Slaugenhaupt, Colette Dib, Sue Povey, Jonathan Haines, An index marker map of chromosome 9 provides strong evidence for positive interference. American Journal of Human Genetics. ,vol. 53, pp. 1279- 1288 ,(1993)
P. Sonigo, A. Elmaleh, E. Brunelle, L. Fermont, A. -L. Delezo�de, V. Mirlesse, Prenatal MRI diagnosis of fetal cerebral tuberous sclerosis. Pediatric Radiology. ,vol. 26, pp. 1- 4 ,(1996) , 10.1007/BF01403693
George Giacoia, Fetal rhabdomyoma: a prenatal echocardiographic marker of tuberous sclerosis. American Journal of Perinatology. ,vol. 9, pp. 111- 114 ,(1992) , 10.1055/S-2007-994681
JOHN P. OSBORNE, ALAN FRYER, DAVID WEBB, Epidemiology of Tuberous Sclerosis Annals of the New York Academy of Sciences. ,vol. 615, pp. 125- 127 ,(1991) , 10.1111/J.1749-6632.1991.TB37754.X
R. S. Kandt, J. L. Haines, M. Smith, H. Northrup, R. J. M. Gardner, M. P. Short, K. Dumars, E. S. Roach, S. Steingold, S. Wall, S. H. Blanton, P. Flodman, D. J. Kwiatkowski, A. Jewell, J. L. Weber, A. D. Roses, M. A. Pericak-Vance, Linkage of an important gene locus for tuberous sclerosis to a chromosome 16 marker for polycystic kidney disease. Nature Genetics. ,vol. 2, pp. 37- 41 ,(1992) , 10.1038/NG0992-37
E.S. Roach, Moyra Smith, Peter Huttenlocher, Mohandes Bhat, Deborah Alcorn, Louise Hawley, Report of the Diagnostic Criteria Committee of the National Tuberous Sclerosis Association Journal of Child Neurology. ,vol. 7, pp. 221- 224 ,(1992) , 10.1177/088307389200700219
C.D. Gresser, J. Shime, H. Rakowski, J.F. Smallhorn, A. Hui, J.J. Berg, Fetal cardiac tumor: A prenatal echocardiographic marker for tuberous sclerosis American Journal of Obstetrics and Gynecology. ,vol. 156, pp. 689- 690 ,(1987) , 10.1016/0002-9378(87)90079-2
Cary O. Harding, Roberta A. Pagon, Incidence of tuberous sclerosis in patients with cardiac rhabdomyoma. American Journal of Medical Genetics. ,vol. 37, pp. 443- 446 ,(1990) , 10.1002/AJMG.1320370402
W. C. Wiederholt, M. R. Gomez, L. T. Kurland, Incidence and prevalence of tuberous sclerosis in Rochester, Minnesota, 1950 through 1982 Neurology. ,vol. 35, pp. 600- 600 ,(1985) , 10.1212/WNL.35.4.600
John F. Smythe, John D. Dyck, Jeffrey F. Smallhorn, Robert M. Freedom, Natural history of cardiac rhabdomyoma in infancy and childhood. American Journal of Cardiology. ,vol. 66, pp. 1247- 1249 ,(1990) , 10.1016/0002-9149(90)91109-J