摘要: Our understanding of the molecular, structural and pharmacological properties GABA(B) receptor has lagged behind that GABA(A) for several decades. This situation changed with recent cloning this receptor, revealing an unexpected highly intriguing complexity both structure function.
elsevier.com
sci-hub.se 参考文章(49)
Fang Liu, Qi Wan, Zdenek B. Pristupa, Xian-Min Yu, Yu Tian Wang, Hyman B. Niznik, Direct protein–protein coupling enables cross-talk between dopamine D5 and γ-aminobutyric acid A receptors Nature. ,vol. 403, pp. 274- 280 ,(2000) , 10.1038/35002014
The Pharmacology of Pain Handbook of Experimental Pharmacology: Vol.130. Springer Verlag: Berlin. (1997). ,(1997) , 10.1007/978-3-642-60777-6
Julia H. White, Alan Wise, Martin J. Main, Andrew Green, Neil J. Fraser, Graham H. Disney, Ashley A. Barnes, Piers Emson, Steven M. Foord, Fiona H. Marshall, Heterodimerization is required for the formation of a functional GABAB receptor Nature. ,vol. 396, pp. 679- 682 ,(1998) , 10.1038/25354
Klemens Kaupmann, Barbara Malitschek, Valerie Schuler, Jakob Heid, Wolfgang Froestl, Pascal Beck, Johannes Mosbacher, Serge Bischoff, Akos Kulik, Ryuichi Shigemoto, Andreas Karschin, Bernhard Bettler, GABAB-RECEPTOR SUBTYPES ASSEMBLE INTO FUNCTIONAL HETEROMERIC COMPLEXES Nature. ,vol. 396, pp. 683- 687 ,(1998) , 10.1038/25360
Barbara Malitschek, Claude Schweizer, Miranda Keir, Jakob Heid, Wolfgang Froestl, Johannes Mosbacher, Rainer Kuhn, Jeremy Henley, Cécile Joly, Jean-Phillippe Pin, Klemens Kaupmann, Bernhard Bettler, The N-terminal domain of gamma-aminobutyric Acid(B) receptors is sufficient to specify agonist and antagonist binding. Molecular Pharmacology. ,vol. 56, pp. 448- 454 ,(1999) , 10.1124/MOL.56.2.448
Andrew Billinton, Antoinette O Ige, Alan Wise, Julia H White, Graham H Disney, Fiona H Marshall, Henry J Waldvogel, Richard L.M Faull, Piers C Emson, GABAB receptor heterodimer-component localisation in human brain Molecular Brain Research. ,vol. 77, pp. 111- 124 ,(2000) , 10.1016/S0169-328X(00)00047-4
Serge Bischoff, Sabine Leonhard, Nicole Reymann, Val�rie Schuler, Ryuichi Shigemoto, Klemens Kaupmann, Bernhard Bettler, Spatial distribution of GABABR1 receptor mRNA and binding sites in the rat brain The Journal of Comparative Neurology. ,vol. 412, pp. 1- 16 ,(1999) , 10.1002/(SICI)1096-9861(19990913)412:1<1::AID-CNE1>3.0.CO;2-D
K Jones, Signal Transduction by GABAB Receptor Heterodimers Neuropsychopharmacology. ,vol. 23, pp. S41- S49 ,(2000) , 10.1016/S0893-133X(00)00145-7
Marta Margeta-Mitrovic, Yuh Nung Jan, Lily Yeh Jan, A Trafficking Checkpoint Controls GABAB Receptor Heterodimerization Neuron. ,vol. 27, pp. 97- 106 ,(2000) , 10.1016/S0896-6273(00)00012-X
Thierry Galvez, Laurent Prézeau, Gérald Milioti, Miloslav Franek, Cécile Joly, Wolfgang Froestl, Bernhard Bettler, Hugues-Olivier Bertrand, Jaroslav Blahos, Jean-Philippe Pin, Mapping the Agonist-binding Site of GABAB Type 1 Subunit Sheds Light on the Activation Process of GABABReceptors Journal of Biological Chemistry. ,vol. 275, pp. 41166- 41174 ,(2000) , 10.1074/JBC.M007848200