Nutraceuticals in Preventive Oncology: Chemical Biology and Translational Pharmaceutical Science

摘要: Cancer poses a major health problem worldwide. Although remarkable progress has been made in basic, clinical, and translational cancer researches the last several decades, treatment outcome for most human cancers is still disappointing. It widely accepted that preventable disease, but evidence-based prevention approach lacking. Natural products with broad spectrum of biodiversity chemical structures represent rich source development novel therapeutic preventive agents. This chapter focuses on recent advances mechanism action natural bioactive components, their pharmacodynamic pharmacokinetic characteristics, targets, implication oncology. The rapid molecular cell biology, genetics genomics, medicine provides better understanding mechanisms structure–activity relationships products. We provide examples, such as ginsenosides, curcumin, genistein, to illustrate importance research challenges