On the use of the Weibull function for the discernment of drug release mechanisms.
作者： Vasiliki Papadopoulou , Kosmas Kosmidis , Marilena Vlachou , Panos Macheras
DOI: 10.1016/J.IJPHARM.2005.10.044
关键词:
摘要: … Carlo simulations indicated that Fickian drug release from Euclidian or fractal matrices can be described with the Weibull function. In this study, the entire drug release kinetics of various …
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Panos Macheras, Aristides Dokoumetzidis, On the heterogeneity of drug dissolution and release. Pharmaceutical Research. ,vol. 17, pp. 108- 112 ,(2000) , 10.1023/A:1007596709657
Eleni Rinaki, Aristides Dokoumetzidis, Panos Macheras, The mean dissolution time depends on the dose/solubility ratio. Pharmaceutical Research. ,vol. 20, pp. 406- 408 ,(2003) , 10.1023/A:1022652004114
Zeev Elkoshi, On the Variability of Dissolution Data Pharmaceutical Research. ,vol. 14, pp. 1355- 1362 ,(1997) , 10.1023/A:1012108402682
E Rinaki, G Valsami, P Macheras, The power law can describe the 'entire' drug release curve from HPMC-based matrix tablets: a hypothesis. International Journal of Pharmaceutics. ,vol. 255, pp. 199- 207 ,(2003) , 10.1016/S0378-5173(03)00079-6
Manthena V.S. Varma, Aditya M. Kaushal, Sanjay Garg, Influence of micro-environmental pH on the gel layer behavior and release of a basic drug from various hydrophilic matrices Journal of Controlled Release. ,vol. 103, pp. 499- 510 ,(2005) , 10.1016/J.JCONREL.2004.12.015
Paulo Costa, JM Sousa Lobo, None, Influence of Dissolution Medium Agitation on Release Profiles of Sustained-Release Tablets Drug Development and Industrial Pharmacy. ,vol. 27, pp. 811- 817 ,(2001) , 10.1081/DDC-100107244
Richard W. Korsmeyer, Robert Gurny, Eric Doelker, Pierre Buri, Nikolaos A. Peppas, Mechanisms of solute release from porous hydrophilic polymers International Journal of Pharmaceutics. ,vol. 15, pp. 25- 35 ,(1983) , 10.1016/0378-5173(83)90064-9
Takeru Higuchi, Rate of release of medicaments from ointment bases containing drugs in suspension Journal of Pharmaceutical Sciences. ,vol. 50, pp. 874- 875 ,(1961) , 10.1002/JPS.2600501018
E Adams, D Coomans, J Smeyers-Verbeke, D.L Massart, Non-linear mixed effects models for the evaluation of dissolution profiles. International Journal of Pharmaceutics. ,vol. 240, pp. 37- 53 ,(2002) , 10.1016/S0378-5173(02)00127-8
KC Sung, Phillip R Nixon, John W Skoug, T Robert Ju, Ping Gao, EM Topp, MV Patel, None, Effect of formulation variables on drug and polymer release from HPMC-based matrix tablets International Journal of Pharmaceutics. ,vol. 142, pp. 53- 60 ,(1996) , 10.1016/0378-5173(96)04644-3