Double-blind placebo-controlled trial of methylphenidate in the treatment of adult ADHD patients with comorbid cocaine dependence.
作者： Karen K. Saules , Howard Schubiner , Eric Pihlgren , Cynthia L. Arfken , Nancy Lockhart
DOI: 10.1037//1064-1297.10.3.286
关键词:
摘要: In this 12-week double-blind placebo-controlled trial of methylphenidate (MTP) versus placebo in 48 cocaine-dependent attention-deficit/hyperactivity disorder (ADHD) adults, the authors sought to determine whether MTP would be safe, control ADHD symptoms, and affect cocaine use. Efficacy indexes revealed significantly greater symptom relief group. There were no group differences self-reported use, urinalysis results, or craving. Because relatively small sample size, results are preliminary. However, we found that improved subjective reports symptoms did not worsen use while participants treatment.
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