Prevalence of Inducible Clindamycin Resistance among Community- and Hospital-Associated Staphylococcus aureus Isolates

摘要: Methicillin-resistant Staphylococcus aureus (MRSA) infections have become common among both hospitalized and nonhospitalized patients. Optimal outpatient therapy for MRSA has yet to be determined, but this matter is complicated by the possibility of inducible macrolide-lincosamide-streptogramin B resistance (MLSBi). We studied prevalence MLSBi in community- hospital-associated S. isolates community-associated (CA-MRSA) identified clinical predictors CA-MRSA MLSBi. Among 402 isolates, overall was 52%, with 50% 60% methicillin-susceptible exhibiting represented 14% all had a lower than (33% versus 55%). The presence skin or soft-tissue infection predictive CA-MRSA, comorbidity Due low clindamycin remains useful option therapy.