An almond-enriched diet increases plasma α-tocopherol and improves vascular function but does not affect oxidative stress markers or lipid levels

摘要: Vascular dysfunction is one of the major causes cardiovascular (CV) mortality and increases with age. Epidemiological studies suggest that Mediterranean diets high nut consumption reduce CV disease risk while increasing plasma α-tocopherol. Therefore, we have investigated whether almond supplementation can improve oxidative stress markers factors over 4 weeks in young middle-aged men. Healthy men (56 ± 5.8 years), healthy (22.1 2.9 years) two or more (27.3 5 consumed 50 g almond/day for weeks. A control group maintained habitual same period. Plasma α-tocopherol/cholesterol ratios were not different between groups at baseline significantly elevated by intervention (p < 0.05). protein oxidation nitrite levels whereas, total-, HDL- LDL-cholesterols triglycerides higher but affected intake. In almond-consuming groups, flow-mediated dilatation (FMD) improved systolic blood pressure reduced after almonds/day weeks, diastolic only conclusion, a short-term almond-enriched diet increase α-tocopherol vascular function asymptomatic aged 20 70 years without any effect on lipids stress. © 2014 Informa UK, Ltd.