A role for the NAD-dependent deacetylase Sirt1 in the regulation of autophagy

作者: I. H. Lee , L. Cao , R. Mostoslavsky , D. B. Lombard , J. Liu

DOI: 10.1073/PNAS.0712145105

关键词:

摘要: … Sirt1 and autophagy in nutrient adaptation and the putative role of both autophagy and Sirt1 … whether there might be a connection between Sirt1 activity and the induction of autophagy. …

参考文章(38)
Udai Bhan Pandey, Zhiping Nie, Yakup Batlevi, Brett A. McCray, Gillian P. Ritson, Natalia B. Nedelsky, Stephanie L. Schwartz, Nicholas A. DiProspero, Melanie A. Knight, Oren Schuldiner, Ranjani Padmanabhan, Marc Hild, Deborah L. Berry, Dan Garza, Charlotte C. Hubbert, Tso-Pang Yao, Eric H. Baehrecke, J. Paul Taylor, HDAC6 rescues neurodegeneration and provides an essential link between autophagy and the UPS Nature. ,vol. 447, pp. 859- 863 ,(2007) , 10.1038/NATURE05853
Su-Ju Lin, Pierre-Antoine Defossez, Leonard Guarente, Requirement of NAD and SIR2 for Life-Span Extension by Calorie Restriction in Saccharomyces cerevisiae Science. ,vol. 289, pp. 2126- 2128 ,(2000) , 10.1126/SCIENCE.289.5487.2126
Isei Tanida, Naoko Minematsu-Ikeguchi, Takashi Ueno, Eiki Kominami, Lysosomal Turnover, but Not a Cellular Level, of Endogenous LC3 is a Marker for Autophagy Autophagy. ,vol. 1, pp. 84- 91 ,(2005) , 10.4161/AUTO.1.2.1697
Akiko Kuma, Masahiko Hatano, Makoto Matsui, Akitsugu Yamamoto, Haruaki Nakaya, Tamotsu Yoshimori, Yoshinori Ohsumi, Takeshi Tokuhisa, Noboru Mizushima, The role of autophagy during the early neonatal starvation period Nature. ,vol. 432, pp. 1032- 1036 ,(2004) , 10.1038/NATURE03029
Thomas Nyström, Role of oxidative carbonylation in protein quality control and senescence The EMBO Journal. ,vol. 24, pp. 1311- 1317 ,(2005) , 10.1038/SJ.EMBOJ.7600599
M. P. Fink, Ethyl pyruvate: a novel anti‐inflammatory agent Journal of Internal Medicine. ,vol. 261, pp. 349- 362 ,(2007) , 10.1111/J.1365-2796.2007.01789.X
Shaday Michan, David Sinclair, Sirtuins in mammals: insights into their biological function Biochemical Journal. ,vol. 404, pp. 1- 13 ,(2007) , 10.1042/BJ20070140
Jianyuan Luo, Anatoly Y. Nikolaev, Shin-ichiro Imai, Delin Chen, Fei Su, Ariel Shiloh, Leonard Guarente, Wei Gu, Negative Control of p53 by Sir2α Promotes Cell Survival under Stress Cell. ,vol. 107, pp. 137- 148 ,(2001) , 10.1016/S0092-8674(01)00524-4
Takahiro Shintani, Daniel J Klionsky, Autophagy in Health and Disease: A Double-Edged Sword Science. ,vol. 306, pp. 990- 995 ,(2004) , 10.1126/SCIENCE.1099993
Shino Nemoto, Maria M Fergusson, Toren Finkel, Nutrient availability regulates SIRT1 through a forkhead-dependent pathway. Science. ,vol. 306, pp. 2105- 2108 ,(2004) , 10.1126/SCIENCE.1101731