Mouse genetic models: an ideal system for understanding glaucomatous neurodegeneration and neuroprotection

作者: Gareth R. Howell , Richard T. Libby , Simon W.M. John

DOI: 10.1016/S0079-6123(08)01122-9

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摘要: Here we review how mouse studies are contributing to understanding glaucoma. We include discussion of aqueous humor drainage and intraocular pressure elevation, because new treatments avoid exposure high will indirectly protect neurons from glaucoma, complement direct neuroprotective strategies. describe models adding both the glaucomatous neurodegeneration development

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