Bioactivation of biomorphous silicon carbide bone implants.

摘要: Wood-derived silicon carbide (SiC) offers a specific biomorphous microstructure similar to the cellular pore of bone. Compared with bioactive ceramics such as calcium phosphate, however, is considered not induce spontaneous interface bonding living Bioactivation by chemical treatment was investigated in order accelerate osseointegration and improve bone ability. Biomorphous SiC processed from sipo (Entrandrophragma utile) wood heating an inert atmosphere infiltrating resulting carbon replica liquid melt at 1450°C. After removing excess leaching HF/HNO₃ preform consisted β-SiC small amount (approximately 6wt.%) unreacted carbon. The again leached HCl/HNO₃ finally exposed CaCl₂ solution. X-ray photoelectron spectroscopy (XPS) Fourier transform infrared analyses proved that oxidation residual surface induced formation carboxyl [COO⁻] groups, which triggered adsorption Ca(2+), confirmed XPS inductively coupled plasma optical emission measurements. A local increase Ca(2+) concentration stimulated vitro precipitation Ca₅(PO₄)₃OH (HAP) on during exposure simulated body fluid, indicates significantly increased activity compared SiC.