Penile fibrotic changes after radical retropubic prostatectomy.

作者: S.J. Ciancio , E.D. Kim

DOI: 10.1046/J.1464-410X.2000.00364.X

关键词:

摘要: Objective To investigate the type of penile deformity, response to treatment and predictive factors for formation fibrotic changes after radical retropubic prostatectomy (RRP). Patients methods Between July 1996 September 1998, 110 men who had undergone RRP a mean (SD, range) 35 (20, 5–145) months previously were evaluated by one physician their erectile dysfunction. Those affected advised initiate medical therapy possible Peyronie’s disease; charts reviewed they interviewed determine outcome. Results Overall, 45 patients (41%) with dysfunction changes, representing 11% all undergoing in specified period. The primary clinical presentation included curvature 42 (93%) ‘waistband’ deformity 11 (24%; some both); palpable plaques present 31 (69%). On assessing outcome 40 men, 16 (40%) felt that condition improved, half unchanged 10% progressed, within follow-up 24 months diagnosis. Of 14 regularly using vacuum constriction device or injection therapy. No significant could be identified, including use intracavernosal before onset, neurovascular bundle resection, operative duration, estimated blood loss pathological tumour grade stage. Conclusions Penile are but undescribed problem RRP. Although predisposing not most stabilized improved during treatment. Corroborative confirmation this association its aetiology will require prospective studies.

参考文章(27)
Steven W. Bigg, Louis R. Kavoussi, William J. Catalona, Role of Nerve-Sparing Radical Prostatectomy for Clinical Stage B2 Prostate Cancer Journal of Urology. ,vol. 144, pp. 1420- 1424 ,(1990) , 10.1016/S0022-5347(17)39758-6
Patrick C. Walsh, Jonathan I. Epstein, Franklin C. Lowe, Potency following radical prostatectomy with wide unilateral excision of the neurovascular bundle. The Journal of Urology. ,vol. 138, pp. 823- 827 ,(1987) , 10.1016/S0022-5347(17)43385-4
Juan A Lopez, Jonathan P Jarow, None, Penile Vascular Evaluation of Men with Peyronie’s Disease Journal of Urology. ,vol. 149, pp. 53- 55 ,(1993) , 10.1016/S0022-5347(17)35997-9
Gerald P. Murphy, Curtis Mettlin, Herman Menck, David P. Winchester, Anna Marie Davidson, National Patterns of Prostate Cancer Treatment by Radical Prostatectomy: Results of a Survey by the American College of Surgeons Commission on Cancer Journal of Urology. ,vol. 152, pp. 1817- 1819 ,(1994) , 10.1016/S0022-5347(17)32392-3
Malcolm Bruce Lindsay, David Moddy Schain, Patricia Grambsch, Ralph C. Benson, C. Mary Beard, Leonard T. Kurland, The Incidence of Peyronie’s Disease in Rochester, Minnesota, 1950 through 1984 The Journal of Urology. ,vol. 146, pp. 1007- 1009 ,(1991) , 10.1016/S0022-5347(17)37988-0
David M. Quinlan, Jonathan I. Epstein, Bob S. Carter, Patrick C. Walsh, Sexual function following radical prostatectomy : influence of preservation of neurovascular bundles The Journal of Urology. ,vol. 145, pp. 998- 1002 ,(1991) , 10.1016/S0022-5347(17)38512-9
Martin K. Gelbard, Frederick Dorey, Kathleen James, The Natural History of Peyronie’s Disease Journal of Urology. ,vol. 144, pp. 1376- 1379 ,(1990) , 10.1016/S0022-5347(17)39746-X
K-K Chew, BGA Stuckey, CM Earle, SS Dhaliwal, EJ Keogh, Penile fibrosis in intracavernosal prostaglandin E1 injection therapy for erectile dysfunction. International Journal of Impotence Research. ,vol. 9, pp. 225- 229 ,(1997) , 10.1038/SJ.IJIR.3900296
Francesco Montorsi, Giorgio Guazzoni Luigi, Luigi Ferini Strambi, Luigi F. Da Pozzo, Luciano Nava, Luigi Barbieri, Patrizio Rigatti, Giuliano Pizzini, Alberto Miani, RECOVERY OF SPONTANEOUS ERECTILE FUNCTION AFTER NERVE-SPARING RADICAL RETROPUBIC PROSTATECTOMY WITH AND WITHOUT EARLY INTRACAVERNOUS INJECTIONS OF ALPROSTADIL: RESULTS OF A PROSPECTIVE, RANDOMIZED TRIAL Journal of Urology. ,vol. 158, pp. 1408- 1410 ,(1997) , 10.1016/S0022-5347(01)64227-7
Jan Byström, Carlos Rubio, Induratio penis plastica Peyronie's disease. Clinical features and etiology. Scandinavian Journal of Urology and Nephrology. ,vol. 10, pp. 12- 20 ,(1976) , 10.3109/00365597609179648