Telomere dysfunction induces metabolic and mitochondrial compromise

作者: Ergün Sahin , Simona Colla , Marc Liesa , Javid Moslehi , Florian L. Müller

DOI: 10.1038/NATURE09787

关键词:

摘要: Telomere dysfunction activates p53-mediated cellular growth arrest, senescence and apoptosis to drive progressive atrophy and functional decline in high-turnover tissues. The broader …

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